Weekly Wha Dat?! March 2nd
by Chris Burton
An excellent advice column I stumbled upon. Greatly appreciated this perspective.
Japanese researchers have confirmed for the first time an association in mice between a genetic mutation and the intractable autoimmune disease lupus erythematosus.
“He wakes up each morning with the pain,” said Bertrand. “His pain is often a 7-plus, and he’s going to experience the pain 24/7 for the rest of his life. Rich was an avid runner, 30 hours per week stuff. Now, he is afraid to exercise for 30 minutes. He is an athlete, but he can only dream of what I did.”
Talking about when she was told by the doctor she had the potential life-threatening condition, she said: ‘ I just thought, “So are we talking a week off or something,” and in the end he [the doctor] just went, “You need to sit down … this means you could end up in a wheelchair, you need to take this seriously.”
“Without healthy niches, the bone marrow cannot make normal blood components,” said Lijun Yang, M.D., an associate professor of hematopathology in the UF College of Medicine. “When you stain lupus patients’ bone marrow for dead cells, it is dramatic. In contrast to normal people, most lupus patients’ bone marrows are full of dead cells. Twenty, 30, 50 percent of their cells are dead.”